The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome.

Genome Res · 2013 · PMC3759718 · PMID 23783273

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marginally significantno p-value reported

Only one signal remains marginally significant after Bonferroni correction (Bonferroni adjusted P -value 0.03), with marker rs160890 on chromosome 5 when only the ASD phenotypic class was considered.

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marginal significanceno p-value reported

This marginal significance does not justify a clear declaration of validation of the SNP–SNP interaction result.

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