Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase.

PLoS Genet · 2013 · PMC3764175 · PMID 24039593

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marginally significantno p-value reported

Analysis of 489 pairs of such neighbor mutations revealed a marginally significant deviation from a random expectation 1⁄2: 270 pairs of mutations are consistent with the model of strand-specific asymmetry of mutations, whereas 219 are inconsistent with this model (P sign test = 0.024).

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