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Depletion of the cellular antioxidant system contributes to tenofovir disoproxil fumarate - induced mitochondrial damage and increased oxido-nitrosative stress in the kidney.

J Biomed Sci · 2013 · PMC3765371 · PMID 23957306

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a decreasing trendno p-value reported
The body weight did not show any significant change although it there was a decreasing trend (Figure 1 a).

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