A new reporter mouse cytomegalovirus reveals maintained immediate-early gene expression but poor virus replication in cycling liver sinusoidal endothelial cells.

We correlated the tdTomato/YFP ratios with survival time and noticed that infected cells with a shorter survival time tended to be cells with a low ratio of tdTomato/YFP expression (Figure 6 B), and Spearman test resulted in a highly significant correlation index (r = 0.28, p = 0.0005), arguing that LSEC-uniLT that expressed relatively more YFP than tdTomato lysed earlier than cells that expressed more tdTomato.

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