Dementia in Down's syndrome: an MRI comparison with Alzheimer's disease in the general population.

J Neurodev Disord · 2013 · PMC3765707 · PMID 23962297

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highly significantno p-value reported

Follow-up pairwise comparisons revealed that compared to their respective control groups without dementia, both DS+ and AD had a highly significant reduction in the volume of the hippocampus, and AD (but not DS+) had a highly significant reduction in the volume of the temporal lobe and a highly significant increase in the volume of the lateral ventricles.

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