Specifically dPEI generated highly significant serum IgG, mucosal IgG and IgA antibody levels, as well as CD4 and CD8 T cell responses capable of producing IFN-γ, IL-2 and TNF-α in splenocyte cultures.
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Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection.
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