The association between GTR and OS reached statistical significance in two studies[ 16 19 ] and showed a trend toward significance in the third study.[ 14 ] The duration of the improved OS was consistently 2–3 months in all three studies,[ 14 16 19 ] suggesting that the benefit may be limited in most patients.
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The value of extended glioblastoma resection: Insights from randomized controlled trials.
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