Barely Significant
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The favorable impact of PIK3CA mutations on survival: an analysis of 2587 patients with breast cancer.

Chin J Cancer · 2012 · PMC3777497 · PMID 22640628

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a favorable trendno p-value reported
Nevertheless, 3 of these studies reported a favorable trend that related PIK3CA mutations with improved clinical outcomes.

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failed to reach significanceno p-value reported
[26] , the mutation status failed to reach significance as an independent prognostic factor of OS.

also in 2,311 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.