Polymorphism of brain derived neurotrophic factor influences β amyloid load in cognitively intact apolipoprotein E ε4 carriers.

When analyzed per genetic group, a highly significant and negative correlation was seen only in the group of BDNF met + ve/APOE ε 4 + ve carriers (DR: r = − 0.62, P = 0.01, and TL: r = − 0.58, P = 0.02) ( Fig. 4 A and B, red lines).

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