The T allele of lysyl oxidase-like 1 rs41435250 is a novel risk factor for pseudoexfoliation syndrome and pseudoexfoliation glaucoma independently and through intragenic epistatic interaction.

Mol Vis · 2013 · PMC3782368 · PMID 24068861

Europe PMC

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marginally statistically significantp=0.06so close (0.05 < p ≤ 0.1)

Finally, when the allelic and genotyping frequencies were separately analyzed between the two sub-phenotypes, i.e., subjects with XFS without glaucoma and subjects with XFS/XFG, the rs41435250 T allele risk magnitude was maintained in the patients with XFS while a marginally statistically significant risk was observed in the XFS/XFG group (OR [95% CI]=1.8 [0.9–3.5]; p=0.06; Table 5 ).

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