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Water decoction of coptidis rhizoma prevents oxidative damage in erythrocytes of mice.

Indian J Pharm Sci · 2013 · PMC3783744 · PMID 24082342

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an increasing trendno p-value reported
Acetylphenylhydrazine-induced mice were treated intragastrically with Coptidis Rhizoma at doses of 0.3, 0.6, and 1.2 g/kg per day for 3 days and at the dose of 0.6 and 1.2 g/kg it showed that there was an increasing trend in membranes cytoskeletal proteins of band I-IV, especially a significant upregulation in band II.

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