Therefore local resistance patterns have to be known for appropriate antimicrobial use.[ 8 ] There are some hospital based data which showed that antibiotic resistance is increasing and will be a greater problem if not tackled properly according to present needs as in other developed countries.[ 9 ] Meta analyses of the drug susceptibility results of various laboratories in India reveal an increasing trend of development of resistance to commonly used antimicrobials in pathogens like Salmonella, Shigella, Vibrio cholerae, Staphylococcus aureus, Neisseria gonorrhoeae, N. meningitidis, Klebsiella, Mycobacterium tuberculosis , HIV, plasmodium and others.[ 5 ] Resistance is an emerging concern for treatment of HIV infection, following the rapid expansion in access to antiretroviral medicines in recent years and national surveys are underway to detect and monitor resistance.
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