Frequency response of a protein to local conformational perturbations.

PLoS Comput Biol · 2013 · PMC3784495 · PMID 24086121

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closest p

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may be significantno p-value reported

Considering that perturbation signal was propagated to regions surrounding the P-loop, such as L4, Q-loop and α4, subtle perturbations in the active site of PTP1B may be significant in global transduction of intraprotein signal [25] .

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