The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach.

J R Soc Interface · 2013 · PMC3785825 · PMID 24047872

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may be significantno p-value reported

It may be significant that T 6 of CGRP, important for agonist activity in both CGRP and AM [ 44 , 50 ], is in close proximity to the C-terminal region of ECL2 where D287 or preferably T288 are its most likely interaction partners.

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