Regorafenib effects on human colon carcinoma xenografts monitored by dynamic contrast-enhanced computed tomography with immunohistochemical validation.

PLoS One · 2013 · PMC3786893 · PMID 24098755

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almost significantno p-value reported

DCE-CT Imaging Biomarkers Significant reduction of plasma volume and almost significant reduction of plasma flow quantified by DCE-CT was observed in the therapy group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.