A polymorphism at position 400 in the connection subdomain of HIV-1 reverse transcriptase affects sensitivity to NNRTIs and RNaseH activity.

PLoS One · 2013 · PMC3788777 · PMID 24098331

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hedged sentence

0.0001

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp<0.0001actually significant

This co-variation is highly significant (p<0.0001), however other residues are likely to play a role as the T400/A376 combination is found in approximately half of the subtype B sequences.

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