Barely Significant
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NF-κB is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptors.

PLoS One · 2013 · PMC3790763 · PMID 24124453

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may be significantno p-value reported
The production of IL-4 may be significant because it could contribute to airway hypersensitivity responses that are common in SCD children [41] – [43] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.