Activation associated ERK1/2 signaling impairments in CD8+ T cells co-localize with blunted polyclonal and HIV-1 specific effector functions in early untreated HIV-1 infection.

PLoS One · 2013 · PMC3797111 · PMID 24143233

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marginally significantno p-value reported

The majority of activated cells expressed perforin, and the p-ERK1/2-refractory subset exhibited only a marginally significant trend towards lower perforin + frequency.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.