Technical Advances in Endoscopic Ultrasound (EUS)-Guided Tissue Acquisition for Pancreatic Cancers: How Can We Get the Best Results with EUS-Guided Fine Needle Aspiration?

80 - 84 Three of the RCTs compare 22 and 25 G needles without any statistically significant differences in diagnostic accuracy, although there was a trend towards significance when using 25 G needles in pancreatic head/uncinate lesions. 81 , 82 One prospective study by Sakamoto et al. 84 showed a clear benefit of the 25 G over the 22 G for uncinate processes with reported diagnostic accuracies of 100% versus 33%.

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