On the role of aggregation prone regions in protein evolution, stability, and enzymatic catalysis: insights from diverse analyses.

PLoS Comput Biol · 2013 · PMC3798281 · PMID 24146608

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highly significantno p-value reported

This yields a Z-score of 9.3 for the 373 of 961 true catalytic residues in the Cata dataset that are in structural contact with TANGO predicted APRs and suggests the number of true catalytic residues in contact with TANGO predicted APRs is highly significant.

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