Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA.

We propose that the CARP2 to -4 proteins, whose repression resulted in more-moderate but still highly significant CpdA resistance, are likely to be part of the same signaling pathway as CARP1 or even associated in a complex.

also in 132,142 other papers