An evolution-based approach to De Novo protein design and case study on Mycobacterium tuberculosis.

PLoS Comput Biol · 2013 · PMC3812052 · PMID 24204234

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an obvious trendno p-value reported

An obvious trend in the PBM sequences is the preference of hydrophobic amino acids over hydrophilic, which were also observed in previous physics-based designs [19] , [24] ; this is mainly due to the biasness of physics-based potential (e.g.

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