highly significantP = 1.8 × 10 − 18
However, although we observed highly significant enrichment of the targets of these TFs for the induced proteins ( P = 1.8 × 10 − 18 overall, Figure 4 G), the enrichment was not nearly so high ( P = 9.4 × 10 − 4 overall, Figure 4 G) for repressed proteins ( Figure 4 E–G).