Barely Significant
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Nitric oxide synthase mediates PC12 differentiation induced by the surface topography of nanostructured TiO2.

J Nanobiotechnology · 2013 · PMC3815074 · PMID 24119372

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highly significantno p-value reported
This finding is highly significant for many applications where nanostructures interact with biological systems, for the understanding of cell-nanostructured surface interaction and for the general understanding of the nano-bio interface.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.