Lactate-modulated induction of THBS-1 activates transforming growth factor (TGF)-beta2 and migration of glioma cells in vitro.

PLoS One · 2013 · PMC3815307 · PMID 24223867

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highly significantno p-value reported

Treatment of U87 or HTZ-349 glioma cells with 20 mM sodium lactate corresponds to levels measured in brain tumor specimen 9 and led to a highly significant increase in glioma cell migration 24 hours after treatment ( Figure 2A, B ).

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