The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5'-untranslated part of mRNA.

Microb Biotechnol · 2009 · PMC3815758 · PMID 21261932

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closest p · 0.2× alpha

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boldest claim

The sentences

highly significantP < 1%actually significant

This was further analysed by fitting a simple model for transcript accumulation (see Supporting Information ), where we found no evidence for a difference in transcript stability ( P > 5%), average lifetime 10 min, but found a highly significant increase ( P < 1%), by at least 18‐fold, in the transcription rate in the LV‐2 UTR strain.

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