New aQTL SNPs for the CYP2D6 identified by a novel mediation analysis of genome-wide SNP arrays, gene expression arrays, and CYP2D6 activity.

Biomed Res Int · 2013 · PMC3819829 · PMID 24232670

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highly significantno p-value reported

However, systematic studies of complex diseases with known nonsynonymous SNPs have not yielded many highly significant results, and many associations implicate nonprotein coding regions.

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