Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective.

Finally, in perhaps the most influential trial of this past year, amantadine, given for 4 weeks to TBI patients who were minimally conscious or in a vegetative state at 4 to 16 weeks following TBI, showed a highly significant effect on accelerating the pace of functional recovery ( Giacino et al., 2012 ).

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