highly significantP < 0.001
Using this median number as the cut-off point, 27 patients with FZD3 ICC score > 321.5 and 8 patients with FZD3 ICC score ≤ 321.5 had recurrent or metastatic CRC after follow-up for 42 months and the association between FZD3 ICC scores and recurrent or metastatic CRC was highly significant (Chi-square test: χ 2 = 13.34; P < 0.001).