highly significantP = 0.04
borderline significantP = 0.12
Although comparison of hydroxyproline content between B6 Tsk /+ females and B6 +/+ females showed that Tsk /+ females had higher hydroxyproline levels, the difference was found not to be significant for Site 1 ( P = 0.50), highly significant for Site 2 ( P = 0.04), and borderline significant for Site 3 ( P = 0.12).