MicroRNAs in Head and Neck Cancer.

Int J Dent · 2013 · PMC3821954 · PMID 24260035

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may be significantno p-value reported

The ratio miR-221 : miR-375 may be significant in discerning malignant HNSCC from normal tissue [ 5 ]. miR-205 has been associated with lymph node metastases [ 5 ].

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highly significantno p-value reported

They concluded that overexpression of miR-21, miR-181b, and miR-345 had highly significant associations with progressive leukoplakia lesions and as such could play a role in malignant transformation and may potentially be useful as an miR signature for identifying leukoplakias at risk of malignant transformation [ 32 ].

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