The combination of atenolol and amlodipine is better than their monotherapy for preventing end-organ damage in different types of hypertension in rats.

J Cell Mol Med · 2009 · PMC3822879 · PMID 19220584

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highly significantno p-value reported

Using this test, we observed that the synergism between atenolol and amlodipine was highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.