Barely Significant
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Rheumatoid arthritis synovial fibroblasts produce a soluble form of the interleukin-7 receptor in response to pro-inflammatory cytokines.

J Cell Mol Med · 2011 · PMC3822945 · PMID 21129157

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highly significantno p-value reported
Such differences are highly significant from a clinical point of view, which is why we strongly advocate further validation of serum sIL-7R as a new clinical biomarker in RA.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.