Barely Significant
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Macrophages heterogeneity in atherosclerosis - implications for therapy.

J Cell Mol Med · 2010 · PMC3822996 · PMID 20629993

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likely to be significantno p-value reported
Macrophages also secrete anti-inflammatory mediators to down-regulate inflammatory responses within the lesion; the consequences of removing all macrophages are therefore likely to be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.