( 138 ) reported a 17% decrease in incident CHD comparing extremes of polymer intake in young/middle-aged women, which almost reached statistical significance.
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( 146 ) observed a small trend toward a decrease in intima-media thickness (IMT), an indicator of the presence of carotid atherosclerosis and an independent predictor of CVD, in middle-aged men with high habitual flavonol intake.
For example, there appears to be an increasing trend in the reduction in UTIs with higher cranberry juice intake, but very few studies have addressed such dose-response relations in a systematic way.