Helicobacter pylori infection is associated with the presence of thyroid nodules in the euthyroid population.

PLoS One · 2013 · PMC3823768 · PMID 24244604

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a decreasing trendno p-value reported

pylori infection showed a decreasing trend as serum FT4 level increased ( P trend = 0.020).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.