Barely Significant
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Psoriasis-associated genetic polymorphism in North Indian population in the CCHCR1 gene and in a genomic segment flanking the HLA-C region.

Dis Markers · 2011 · PMC3826380 · PMID 22182809

Europe PMCDOI
1
hedged sentence
0.0000
closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 10-9actually significant
Genotyping of 419 psoriasis families further revealed that CCHCR1*WWCC (four SNPs, 2 each in exons 4 and 10) and HLA-Cw*6 allele were associated with psoriasis [4]. A genome scan of the 220-kb region (at chromosome 6p21) across 171 family-based trios of European origin, identified 59 SNPs (18 in coding and 41 in non-coding regions), of which two SNPs (n.7 and n.9 lying 7 and 4 kb proximal to HLA-C, respectively) were found to exhibit highly significant association (p < 10-9 ), sug- gesting these two SNPs as markers for psoriasis sus- ceptibility [37].

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