Barely Significant
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Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology.

Part Fibre Toxicol · 2013 · PMC3830505 · PMID 24225053

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highly significantno p-value reported
There was a slight reduction in bioactivity due to purification and a highly significant decrease as a result of functionalization, even though carboxylated MWCNT were still effectively taken up by macrophages in vitro and in vivo as demonstrated in other studies [ 25 , 29 ].

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