Molecular phenotypes in triple negative breast cancer from African American patients suggest targets for therapy.

While the associations with specific pathways such as the IGF1 (p = 0.016) signature, the BRCA deficiency signature (p = 0.095) or the genomic grade index (p = 0.040) were statistically borderline significant and visually less pronounced, ( Figure S4A–C ) we could more clearly confirm the associations with TNBC subtypes published by Lehmann and colleagues despite the small number of samples (p = 0.07, 0.009 and 0.008 for mesenchymal stem cell, luminal androgen receptor and basal 1 signatures, respectively, Figure S4D–F ) [9] .

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