DNA Methylation Changes during In Vitro Propagation of Human Mesenchymal Stem Cells: Implications for Their Genomic Stability?

Stem Cells Int · 2013 · PMC3833027 · PMID 24288545

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highly significantno p-value reported

DNAm patterns were overlapping and maintained throughout both long-term culture and ageing, and highly significant differences were observed only at specific CpG sites, associated with promoter regions, especially in homeobox genes and genes involved in cell differentiation [ 83 ].

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