Barely Significant
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High environmental ozone levels lead to enhanced allergenicity of birch pollen.

PLoS One · 2013 · PMC3835901 · PMID 24278250

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highly significantno p-value reported
A highly significant and positive correlation of the variables UI (n = 40), temperature (n = 16) and NO 2 -concentration (n = 40) could be observed ( Fig. 2 A, B, C).

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an increasing trendno p-value reported
pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement yes pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY Introduction Epidemiological studies show an increasing trend in allergies, leading to a major health problem.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.