HLA-A 31:01 and HLA-B 15:02 as genetic markers for carbamazepine hypersensitivity in children.

Clin Pharmacol Ther · 2013 · PMC3839910 · PMID 23588310

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highly significantno p-value reported

A highly significant association with CBZ-HSS and MPE was also observed for the HLA-A*31:01 proxy SNP rs1061235 with 14 (33%) CBZ hypersensitivity cases and only six (6.6%) control patients carrying the T allele (combined OR: 9.45; P=2.6×10 −5 ; Table 2 ).

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