Barely Significant
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Paratuberculosis vaccination causes only limited cross-reactivity in the skin test for diagnosis of bovine tuberculosis.

PLoS One · 2013 · PMC3841166 · PMID 24303029

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp<0.0001actually significant
However, highly significant differences (p<0.0001) were observed between the initial testing and the following 2 years testings in the VH.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.