Obstetric and birth outcomes in pregnant women with epilepsy: A hospital-based study.

In India, with the exception of phenobarbitone, a similar pattern of older AED use has been reported.[ 20 ] The use of VPA has been associated with increased risk of malformation compared to use of CBZ, PHT or LTG.[ 8 20 25 ] A recent report from Australia suggests a decreasing trend of VPA being prescribed in WWE, which was reflected in a similar downward trend in fetal malformation.[ 26 ] Likewise, an analysis of several specialty centers in the USA and UK shows a decline in WWE being treated with VPA.[ 23 ] VPA is still commonly prescribed among our patients and it would be interesting to look at the trend in prescribing in such patients in the future in response to current awareness of the effects of VPA.

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