Comparison of first choice accuracy (per cent correct trials) for control and GluN1 Δ DGCA1 mice revealed a highly significant main effect of genotype ( F 1,19 = 12.04; p < 0.005), a significant main effect of block which reflected reversal learning across blocks ( F 5,95 = 34.56; p < 0.0001), and a significant genotype by block interaction ( F 5,95 = 4.01; p < 0.005; figure 3 a ).
Inspection of the total number of errors made on these S− start trials also revealed a marginally significant difference between the two groups ( t 19 = 2.09; p = 0.050; data not shown).
A similar analysis for total errors also showed an overall effect of start location ( F 2,38 = 32.48; p < 0.0001), but the genotype by start location interaction just failed to reach statistical significance ( F 2,38 = 2.99; p = 0.06, data not shown). 4.