Signatures of selection identify loci associated with milk yield in sheep.

The average allele substitution effect (T to A substitution) was highly significant (+ 10.1 l milk ± 4; P = 0.02 for the Altamurana breed and + 22.9 l milk ± 8; P = 0.005 for the Sarda), this corroborating the hypothesis that the PALMD T allele at c.547 T > A of the accession NM_001035079.1 causes a reduction in the sheep ability to produce milk.

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