Barely Significant
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Sex differences in opioid analgesia and addiction: interactions among opioid receptors and estrogen receptors.

Mol Pain · 2013 · PMC3844594 · PMID 24010861

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may be significantno p-value reported
It is postulated that the organizational effects of steroids during critical periods in development, which determine gender-related distinctions, may be significant in the male–female differences [ 81 ].

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