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Have guidelines affected ear, nose, and throat specialists' diagnoses and the prescription of antibiotics for acute otitis media?

Iran J Otorhinolaryngol · 2012 · PMC3846213 · PMID 24303386

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an interesting trendno p-value reported
However, the studies do show an interesting trend in that prescription of broad-spectrum antibiotics for AOM steadily increased from 1998 to 2004 but declined after the guidelines were introduced ( 23 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.