Effect of GSTM2-5 polymorphisms in relation to tobacco smoke exposures on lung function growth: a birth cohort study.

BMC Pulm Med · 2013 · PMC3846453 · PMID 24004509

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marginally significantno p-value reported

Since active smoking only had marginally significant effects on FEV 1 and FEV 1 /FVC at age 18 in the Isle of Wight (IOW) cohort (unpublished observations), the effect may only be detected in those with a genetic susceptibility, acting through an epigenetic mechanism.

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