Barely Significant
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Meta-analysis of randomized controlled trials on the efficacy and safety of intracoronary administration of tirofiban for no-reflow phenomenon.

BMC Cardiovasc Disord · 2013 · PMC3847195 · PMID 24016038

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an increasing trendno p-value reported
Although it didn’t reach the statistical significance, an increasing trend of bleeding was observed comparing with the conventional drugs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.